BiomedGrid

  En-Bloc Transurethral Resection of Non-Muscle- Invasive Bladder Cancer. Current Evidence and Glimpses into the Future   Abstract Background: The purpose of this review was to summarize the current evidence on en-bloc transurethral resection (eTURB) of non-muscle-invasive bladder cancer compared to conventional TURB (cTURB) with a particular emphasis on ongoing randomized trials. Materials and methods: A PubMed/MEDLINE search of the English-language literature from its inception until June 2019 using the following terms in isolation or combination “bladder cancer”, “en bloc”, “TURB” and “resection” was performed. Evidence synthesis: Compared to cTURB, eTURB has been shown to achieve higher rates of detrusor muscle (>95%) and better quality of the specimen for pathological evaluation. Complication rates and perioperative outcomes are comparable between the two techniques. Moreover, eTURB seems to achieve lower recurrence rates. However

  The Association Between Oxidative Stress, Inflammation and Diabetes Opinion The concept of stress has been studied over many decades. An individual can research various forms of stress such as psychological, physiological, emotional, acute, and chronic. Other terms related to stress are daily hassles and oxidative. Holmes & Rahe [ 1 ] and Selye [ 2 ] reported that stress is a force or, are forces that place demands on an individual and as a result a series of responses occur. Selye [ 2 ] also reported that the forces, also termed stressors, evoke positive or negative responses in an individual. The aim of this manuscript is to describe the association between oxidative stress and diabetes mellitus. Diabetes mellitus (DM) is a disorder related to impairment in glucose metabolism. In 2013 a report from the World Health Organization (WHO) indicated that globally, the number of people with chronic diseases such as diabetes was increased [ 3 ]. The world-wide mortality rate for peop

  Exhibition of Postural Time-Force Parameters in Varying Severity of Osteoarthritis of Knee During Performing Sit-To-Stand Testing Abstract Background: Knee osteoarthritis (OA) is an irreversible leading cause of disability in elder. Clinical and research assessment for knee osteoarthritis often use radiographic finding to determine the disease severity. But recently research found that radiographic diagnosis couldn’t reflect the functional activity of life capacity of patient with knee osteoarthritis. Load distribution influence functional capacity of patient with knee osteoarthritis. It is important to know the correlation between performance and functional capacity of knee osteoarthritis patients. Purpose: In this study, a sit-to-stand task was chosen to compare the force-plate measured time-force parameters and weight bearing asymmetry degree in knee osteoarthritis patients with different functional severity. Method: Study content sit-to-

    Association Between Timp-3/Angiotensin II, Profile and Cardiac Remodeling in Patients with Essential Hypertension and Heart Failure with Mid- Range Ejection Fraction Abstract Background and Aims: Arterial hypertension (AH) is a leading cause for heart failure with mid-range ejection fraction (HfmrEF). The aim of our study was to: 1. Measure levels of tissue inhibitor of matrix metalloprotease-3 (TIMP-3) and Angiotensin II (AII) in sera of patients with AH and HFmrEF. 2. In sera of controls. Material and Methods: 56 patients with AH and HfmrEF were examined, mean age 65.62±9.69; and 22 age and sex matched healthy subjects, mean age 56.4±5.53. 41 of patients were with hypertension mediated organ damage and 15 were without. Patients were divided in two subgroupssubjects with left ventricular hypertrophy (n=32); (HFmrEF+LVH) and subjects without left ventricular hypertrophy (n=24); (HFmrEF-LVH). ELISA was used for measuring AII and TIMP-3.