BiomedGrid

  Medically Complex Children; Defining A Specialty Opinion Medically complex children can be defined as subset of pediatrics with multiple co-morbidities, technology dependence, increased healthcare needs, and significant functional limitations [ 1 ]. The proportion of medically complex children requiring services in the pediatric healthcare environment is rapidly increasing [ 1 ]. In addition, medically complex children have the potential to significantly impact institutional indicators of success including hospital-readmissions and mortality rates, as well as healthcare costs [ 2 , 3 ]. Significant vulnerability as well as increased reliance on artificial and technological devices for survival may also disproportionally impact other quality measures of success including nosocomial infections, ventilator associated pneumonia, central line associated blood stream infections, surgical site infections, catheter associated urinary tract infections, pressure ulcer ra...

  Screening of Oat (Avena Sativa) Varieties in Saline- Sodic Soil Abstract Oat has much privileged sodium ion levels than wheat, soybean, cotton, and other seasonal crops. Oat cultivation is still well thought-out to stand for a supportive biological assess to recover saline lands due to its high capability to accrue salt ions in its straw, which is widely used as forage for livestock. Seeds of Oat (Avena sativa) were sown in a pot study to different combinations of salinity and sodicity [S0=4.70dSm -1 + 19.12 (mmol L -1 ) 1/2 , S1= 9.02dSm -1 +30.65 (mmol L -1 ) 1/2 and S 2 = 11.35 dSm -1 +34.69 (mmol L -1 ) 1/2 ]. Seven oat varieties namely Bulbin, S-2000, Dilawar, PD2LV65, No.667, Bob and Cyprus were used for screening against salt tolerance. The leaset % decrease in grain yield (35.24) was attained in S-2000 oat variety than other varieties. Therefore, this oat variety showed minimum loss due to toxic effects of salinity cum sodicity. Dilawar oat...

  Estrous Cycle Ratio as a Reproductive Index in the Rats Abstract Estrous cycle is an endogenous rhythm. Previously, studies have evaluated and analyzed the cycle based on its regularity and length and diestrus proportion. The aim of the review is to introduce estrous cycle ratio as a reproductive index and highlight its relevance. Twenty murine studies were retrieved from electronic databases published between 1999 and 2019. Estrous cycle ratio was calculated according to the method of [ 1 ]. The result shows that the average estrous cycle ratio is 0.81 with a nadir of 0.5 and a zenith of 1.5. Increase in estrous cycle ratio may signify prolongation of follicular phase length and delay in ovulation. Decrease in estrous cycle ratio may indicate delay in luteal regression with attendant delay in the initiation of new folliculogenesis. Therefore, estrous cycle ratio is an estrous cycle evaluation index. Keywords: Estrous Cycle Ratio; Follicular Phas...

  Use of Laboratory Animals in A Pre-Clinical Trial: A Critical View of the Biomodels Development and Application  Abstract The scientific use of laboratory animals throughout history demonstrates changes in their vision and applicability, specifically from a moral, ethical and current legislation. In the Laboratory Animal Science Division of the Cellular Biology Laboratory, the development of experimental models and the performance of pre-clinical tests emphasizes the 3Rs principle of refinement in relation to equipment and methodologies. Thus, we transform the point of view over animal model as a Bioreactor for a Biomodel, being able to associate clinical/behavioral methods, consequently, to increase the welfare animal, reproducibility and confiability of the results. Keywords: Experimental model; Animal welfare; Bioresearch Opinion The use of animal models in research has been done since Antiquity...

  Analytic Hepatic Deterioration in Rectal Cancer: Liver Steatosis Vs Disease Progression Introduction Hepatic steatosis is a phenomenon that is often objectified in imaging tests that, if there is no analytical alteration of the hepatic profile, does not need further follow-up. It can be caused by chemotherapy treatment, so in oncological patients should be monitored more closely. We present the case of a patient treated with capecitabine who, once the treatment was finished, began to increase bilirubin and transaminases, showing an increased diffuse hepatic steatosis in an MRI. Clinical Case A man of 65 years old diagnosed of rectal adenocarcinoma, started chemoradiation (capecitabine) in July 2018. Good tolerance of treatment. After finishing treatment, bilirubin started to elevate (2.4), without fever or clinical infection. Surveillance at next week was performed, showing progressive elevation of Br, without use of new drugs and mor...

   Monitoring of Organophosphorus Pesticides in Brazilian Food   Abstract The accumulation of agrochemicals in agricultural products is a major concern since the plants act as intermediates in the transport of soil, water, and air contaminants to humans and fauna. The assessment of pesticide residues in food has become a priority objective, ensuring the quality of food and protecting consumers against possible risks. Brazil has legislation on pesticides, but monitoring is still far from other countries, as is the case in the USA and Europe. Therefore, it is necessary to establish better practices for the evaluation of pesticide residues in food. Introduction The monitoring of pesticides in the environment is a very important tool in the characterization and management of environmental risks resulting from the use of these products under real conditions [1], as well as a form of measurement in minimizing t...

  Histological Study of Effect of Ethanol Stem Extracts of Homalium Letestui in Paracetamol Induced Injury in Albino Rat, Using Various Staining Techniques Abstract Introduction/Aim: The use of medicinal plants has attained a commanding role in health system all over the world. This involves the use of medicinal plants not only for the treatment of diseases but also as potential material for maintaining good health and conditions. Many countries in the world, that is, two-third of the world’s population depends on herbal medicine for primary health care. Homalium letestui is an evergreen tree. The plant has been of immense benefit to traditional users. A bark-decoction, combined with other medicinal plants, is taken by draught for orchitis, and bark-scrapings enter a prescription given to a newly delivered woman. In this study the histological effect of the ethanol stem extract of Homalium lestetui on rat paracetamol induce liver injury was carried o...