BiomedGrid

  Epidemics with a Path to Quantum Epidemics Abstract Classical epidemics are based on classical probability. In this paper, we review classical epidemics, the generalization of which to quantum probability is fundamentally interesting. Keywords:  epidemic, quantum probability, stochastic models Introduction SIR is an effective means of analysing a standard infection scenario, whereby (S) stands for the susceptible people who are healthy but can contract the disease, infectives (I) accounts for those who have contracted and can transmit a disease, and the removed cases (R) accounts for a population that leaves the infection either through death or recovery. Investigated the SIR model using the analytical matrix method in which they determined the distribution of the final stage of the process. Epidemic models evaluate the manner in which infectious diseases spread in a population. They also made several interesting measures of the dimensions of the epidemic. However, the model has not

  Addressing Lifestyle Issues: Thoughts on Adopting a Systems Approach Opinion Lifestyle is a social phenomenon. It is the interests, way of thinking, way of living, or orientation to life of an individual, group, community or culture. Lifestyle results from several interacting factors that produce a predisposition to act in certain ways or a certain style of behaving toward one’s environment, broadly speaking. One useful way to look at lifestyle is to consider lifestyle as a mediating variable between values and observed behavior. In other words, lifestyle is a way of expressing one’s values toward a thing or phenomenon [ 1 ]. Take for example health, a healthy life style emanates from the value one places on eating a balanced diet, shopping for the ingredients that make up this balanced diet, regular exercise, avoiding harmful habits, seeking out useful information on achieving and maintaining a healthy lifestyle and the value placed on the opinion of significant others that may infl

  Organ Trafficking as a Criminological Problem Abstract The author draws attention to the illegal trade in human organs, which has been increasing in recent times due to increasing demand. Means and methods of searching for organ donors, recruitment, transplantation technologies are improving. The volume of trafficking in human organs, the damage to specific individuals and the profits made illegally are difficult to quantify. Under these circumstances, the value of human life is leveled. Different approaches and methods are applied to the materialized determination of human life and the value of its organs, thus the volume of organs removed, and their prices are evaluated differently. The trafficking of human organs as a criminological problem is becoming more and more important in recognizing human beings as a fundamental value in today’s society. Keywords:  Human Being; Human Organs; Organ Trade, Price of Organs; Transplantation; Values Introduction The cost of human life and its o

  Diabetes-Cancer Risk: Hyperglycemia on DNA Damage and Repair Abstract Increased risk of certain cancers has been reported in populations with diabetes mellitus. Ample research supports the notion that diabetic conditions generate excessive amounts of reactive oxygen species, thus resulting in oxidative DNA damage. Recently, several discoveries have shown that cells grown in high glucose conditions also have defective DNA damage response and repair pathways. When considered together, the dual concerns of elevated oxidative DNA damage and aberrant DNA damage response and repair underscore the importance of maintaining tight glycemic control in patients with diabetes mellitus and cancer Keywords:  Cancer; Diabetes; DNA damage response pathway; NEK1; ATM; ATR; Hyperglycemia Abbrevation:  ATM: Ataxia Telangiectasia Mutated; ATR: ATM and Rad3-related kinase; NEK1: Nima A Related Protein Kinase 1; H4AXphosphorylation of H4AX at Ser 139; IR: Ionizing Radiation; CIN: Chromosomal Instability;

  Evaluation of Hexarelin Effects on Epileptic Seizures, Hippocampal Neuronal Damage and Memory Impairment after Pentylenetetrazole-Induced Acute Model in Rat Abstract Recent studies have demonstrated that ghrelin receptors have antiepileptic effects. The aim of this study was to investigate the effect of ghrelin receptor agonist hexarelin on pentylenetetrazole (PTZ)-induced seizures and post-seizure hippocampal damage. In our study, we used 42 male 230-250 g Wistar Albino rats. Animals were divided into seven groups as control, saline (PTZ; 1 ml/kg serum physiologic), positive control (5 mg/kg diazepam), 50 μg/kg, 100 μg/kg, 200 μg/kg and 400 μg/kg hexarelin. 30 min after drugs administration at the indicated doses, PTZ was administered 45 mg/kg to induce an epileptic seizure. The animals were observed for 30 min. Seizure stages (according to the Racine Scale) and first myoclonic jerk times (FMJ). 24 hours after PTZ injection, passive avoidance test was performed, and then brain tissu