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Biomedical Science and Research Journals | Young-Onset Colorectal Carcinoma: Is This A Single Entity or A Two Age Group with Different Pathological Findings and Molecular Profiles?

  Young-Onset Colorectal Carcinoma: Is This A Single Entity or A Two Age Group with Different Pathological Findings and Molecular Profiles? Abstract Context:  Although the national incidence of colorectal cancer (CRC) has decreased in recent years, mortality has increased among those younger than 50 years. While CRC has been widely studied, there have been few studies analyzing specific pathologic parameters in patients with youngonset CRC (YO-CRC). YO-CRC is one of the hallmarks of hereditary CRC syndromes. Objective:  The primary aim of this study was to identify the clinical, pathological, and molecular features of YO-CRCs. Design:  All patients with a diagnosis of YO-CRC treated surgically at our institution between August 2016 and February 2020 were included in our study. The age distribution, race, ethnicity, history of hereditary cancer syndromes, tumor location, grade, stage, size, and molecular findings were analyzed. We divided the patients into four groups according to the r

Biomedical Science and Research Journals | Assessing Citation Bias in Scientific Literature

  Assessing Citation Bias in Scientific Literature Abstract Our objective was to provide a further test of possible citation bias or confirmation bias in science based on differential outcomes of two articles published between 1979 and 2013. The two articles used here formed a natural experiment because the articles were from the same author and concerned similar topics except one article had more positive results for its participants. Based on Google Scholar citations, citation rates were compared using binomial tests, including normal approximation z scores, and one-sample chi-square tests. Between the two articles, the one that presented more favorable findings was cited far more often than the one with less positive results, providing empirical support for the existence of citation or confirmation bias, which may result in lower quality and less comprehensive literature reviews. Keywords:  Citation Rates; Citation Bias; Confirmation Bias; Research Methodology; Literature Reviews; Q

Biomedical Science and Research Journals | This Moment of Review of Humanity Reaches Up How Eat and to the Ways of Getting Food?

  This Moment of Review of Humanity Reaches Up How Eat and to the Ways of Getting Food? Opinion The Covid 19 pandemic has generated a special moment for contemporary humanity. It has placed us in a place of complexity, uncertainty accompanied by a need for abrupt changes in habits, although in principle temporary. One of these forced changes has been preventive social isolation, a tool used in almost all countries as a means to reduce the escalation of infections. Staying at home without going to work, without attending the usual recreations, without being able to compulsively go to the supermarket, forced us directly or indirectly to rethink our basic needs. In that conscious or unconscious classification, health, shelter from a house and the feeding was presented as the first. Something logical but with the hustle and bustle that the so-called Western way of life poses to us daily, they seem to mix with many other more superfluous and therefore unnecessary or dispensable in the face

Biomedical Science and Research Journals | Triggered Alice in Wonderland-like Disturbed Visual Body Sensations Arbitrarily Inducible by Firm Hand Position in a Pillow in Bed Since Age 6

  Triggered Alice in Wonderland-like Disturbed Visual Body Sensations Arbitrarily Inducible by Firm Hand Position in a Pillow in Bed Since Age 6 Introduction “Alice`s Adventures under Ground” [1] wrote in 1864 the roman of Alice in Wonderland Lewis Carroll. In 1955 the British psychiatrist John Todd (1914-1987) described the strange state of the micro- and macrosomatognosy, changed perception of the body picture and described it as Alice in the wonderland syndrome. John Todd described it in 1955 and gave him in his publication the literary name. The first description of the state became from Lippman et al. AIWS encloses the distortion of the body picture, the form of objects, the feeling of the time expiry and zooming the surroundings. In the book Caroll these changed changes of the body form were interpreted as somatosensoric dysfunction. The true origin is still unknown. AIWS was described in connection with many different infection illnesses like malaria, zicavirus, Varizella-induce

Biomedical Science and Research Journals | A Case Report of a Glomangioma in an Unusual Location and Review of the Literature

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  A Case Report of a Glomangioma in an Unusual Location and Review of the Literature Abstract Glomangioma or glomus tumors are rare neoplasms of the glomus body, which are located in the stratum reticularis of the dermis throughout the body. Its location on the elbow is unusual and presents a diagnostic challenge. It manifests clinically by a triad of pain, tenderness and cold hypersensitivity. We present a case of 75-year-old male who presented with a very painful nodule over the left elbow for the past 3 years. Dermoscopy showed an angiomatous nodule. After local excision, histopathology revealed sheets of epitheloid-like ovoid cells, disposing around dilated and congestive vascular structures without nuclear pleomorphism or mitotic activity. On immunohistochemistry, glomus cells were positive to smooth muscle actin, characteristic of a glomus tumor. Keywords:  Glomus Body; Elbow; Glomus Cells; Glomangioma Introductions Glomus tumors are rare benign mesenchymal neoplasms of the skin

Biomedical Science and Research Journals | Approaches to Research and Clinical Practice Relating to Zinc Deficiency

  Approaches to Research and Clinical Practice Relating to Zinc Deficiency Introduction Zinc deficiency is common in developing countries and affects over 2 billion people worldwide. Wessells and Brown reported [1] that an estimated 17.3% of the global population is at risk of inadequate zinc intake, with the regional estimated prevalence of inadequate intake ranging from 7.5% in high-income regions to 30% in South Asia. Zinc deficiency often accompanies various conditions and diseases, and can affect the elderly, pregnant women, lactating women, patients with chronic diseases, such as diabetes mellitus, liver disease, kidney disease, and inflammatory bowel disease, and during the administration of chelators [2]. Zinc is essential for the function of more than 300 different enzymes and transcription factors. Manifestations of zinc deficiency include, for example, dermatitis, delayed wound healing, impaired taste, loss of appetite, hair loss, fertility issues, increased susceptibility t