BiomedGrid

  Epidemiology and Pattern of Clubfoot in Enugu, South- East Nigeria Summary Background:  clubfoot is a musculoskeletal birth defect of the foot and ankle that affects a lot of children in the world which can pose ambulatory and activity challenges to affected individual when not treated. Aim:  To evaluate the epidemiology and pattern of clubfoot at Enugu, Southeast Nigeria. Study Design:  A retrospective epidemiological study. Methodology:  Ninety-six case notes of patients managed for clubfoot between January 2014 and December 2017. Simple statistical methods like frequency, percentage and mean were used for data presentation and analysis. Results:  Idiopathic clubfoot had highest prevalence of 92%, secondary clubfoot 6% and positional clubfoot 2%. Male gender had occurrence rate of 56% and female 44%. Bilateral clubfoot has greater dominance with a prevalence rate of 75% and unilateral clubfoot 25%. 16% responded to plaster cast application without requi...

  The Sufferings of Cancer Patients Infected by SARS-CoV-2 Opinion The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has drawn attention in the world in early 2020. This is an infectious disease occurs by an unusual type of coronavirus, spreads easily and has a significant mortality rate. Among different types of coronaviruses, some cause mild sickness i.e., cold, sneeze while others can be more serious with severe complications. This virus spread from person to person, particularly when a COVID-19 patient delivers droplets with sneezes or coughs. The common symptoms of coronavirus include a high temperature of above 37.80C, continuous cough, and a loss of/change in normal sense of taste or smell. In this write-up, we have tried to accumulate the currently available information on the outcome of SARS-CoV-2 infection on patients with cancer comorbidities [1]. The immune system protects body against illness and infection ...

  Choroidal Metastasis of Breast Cancer: A Case Report and Literature Review Summary Choroid is a very rare site of metastases but the most primary cancers leading to choroidal metastases are breast cancer then lung cancer. Generally, choroidal metastases occur late the course of cancer in the presence previously of other metastatic sites, and they were associated with poor prognosis. We report the case of a patient followed in Medical Oncology Department of Fes, for breast cancer who presented visual disorders leading to the diagnosis of choroidal metastasis. The aim of this work is to report the rarity of this metastatic site, describe the clinical, and radiological features in addition to therapeutic and prognostic aspects. Keywords: Choroid metastasis; Breast cancer; Chemotherapy; Radiotherapy; Prognosis. Introduction Breast cancer can metastasize on many sites, but the choroid is an uncommon site [1]. The longer survival of patients with metastatic disease as well as advances ...

  Gastrointestinal Symptoms of COVID-19 Abstract COVID-19 caused by SARS-COV-2, first reported in China in December 2019, has now affected the entire world. Some studies have found that gastrointestinal symptoms are common clinical symptoms in COVID-19 patients. To explore the correlation between gastrointestinal symptoms and symptoms, diagnosis, treatment, and prognosis of COVID-19 is of great significance. Keywords: COVID-19, Digestive system Introduction Novel coronavirus (COVID-19 pneumonia) is causing a global pandemic, which is also one of the major challenges facing human health at present. It is caused by novel coronavirus (2019-nCoV) infection and belongs to β- coronavirus (including SARS-CoV and Severe Respiratory Syndrome Coronavirus (MERS-CoV)). After infection, patients usually have fever and respiratory diseases, but some patients may have gastrointestinal symptoms such as diarrhoea, vomiting and abdominal pain. Digestive Symptoms in Patients with COVID-19 At present,...

  Agricultural Plants and Their Antimicrobial Activities - A Mini Review Abstract Agricultural plants are rich in antioxidants and can be effectively used as antimicrobial agents. This review emphasizes the role of plants such as hemp, kenaf, jute, flax, and sisal that contain many bioactive compounds. They are known for antimicrobial, which provides further insight towards a better environment, health, and prevention from infectious diseases. Keywords: Agricultural plants; phytochemicals; antimicrobial activity Introduction Agricultural plants are major sources of natural fibers. Plants contain many bioactive compounds and are a great source of antimicrobial agents [1]. Microbial contamination poses a serious threat to human health Plants with medicinal values have always been effective to cure different diseases caused by microorganisms. Centers for Disease Control and Prevention (CDC) has reported that 90 % of foodborne human illness is attributed to bacteria. The most important...

  Negative Impact of Obesity on Dialysis Efficiency: A Prospective Cohort on Lebanese CKD Patients Abstract Background:  Obesity is considered as a risk factor in chronic kidney disease (CKD), as it may worsen renal complications and progress to advanced stages of the disease. Aims: To investigate whether the efficacy of dialysis is affected in obese CKD patients. Methods:  we followed the main biological factors in dialysis patients for six months. Patients were grouped based on their sexes and body mass indexes (obese, or normal-weighted) and blood samples measurements were performed before and after dialysis. Results:  The elimination of creatinine and urea by dialysis is more significant in normal-weighted than obese women. Elimination of potassium and sodium have tendency to be also more effective in normal-weighted women. No significant differences were found between normal-weighted and obese men regarding creatinine, urea, potassium, and sodium elimination. Ho...

  Increased Serum Glucose is not a Covid-19 Mortality Predictor in Elderly Patients Abstract COVID-19 is causing a current pandemic with high mortality, in which older age is an important risk factor. Few studies have examined whether risk factors for death by COVID-19 are similar in elderly and younger patients. We reviewed electronic hospital records of all consecutive adult patients admitted and analyzed reported COVID-19 mortality risk factors stratified by age group (under 60 vs. 60 and over). In univariate analyses admission date, sex, age, oxygen saturation, hyperglycemia (defined as admission glucose>180mg/dl) and lactate dehydrogenase were associated with COVID-19 mortality in younger patients, while only sex, oxygen saturation and lactate dehydrogenase were associated with mortality in the elderly. Mortality for younger subjects without hyperglycemia was 39.1%, while it was 66.7% in for younger subjects with hyperglycemia, similar to the mortality in the 60 and over ag...