BiomedGrid

Wheat-gluten-desirable-or-dangerous-genes Abstract My opinion is issued to collect and broaden the information about gluten, or more precisely, whether its presence and properties should raise concerns. Knowledge about gluten has expanded considerably over the last dozen or so years. It is known that it is a large polymer consisting of a mixture of proteins. Gluten occurs in popular cereals such as wheat, spelt, barley, rye and oat. Works carried out by cereal breeding institutes require a continuous control of the presence of various forms of these proteins in wheat grain, because, firstly, there is a need to obtain fertile varieties with high grain quality parameters, and secondly, to improve the physical and chemical properties of farinaceous products. As it turned out, gluten, which brings many positive aspects in the breeding process of cereals, as well as in the production of bakery products, can become a cause of many problems for humans. According to many authors, apart from ce...

  Plant Toxins Abstract Plant toxins are generally the metabolites produce through plants to protect themselves against different threats like insects, predators and microorganisms These toxins found in food plants is due to natural or new reproduction methods which enhance defensive mechanism. The plant part which may cause toxic effects includes roots, tuber, stem, fruits, buds and foliage. Natural toxins are present in numerous types of plants and these are ingested as food and when consumed in large quantity and not cook properly leads to food poisoning. These toxic substances when ingested can be potentially harmful to human health. Some plants produce phytotoxins that can severely harm or destroy any herbivore. Such as toxic proteins which have a role in defense against pathogens and insects. Such as ricin and rRNA N-glycosidase which have the potential to be used as bio-threat agents. They can be modified to exemplify improved affinity and efficacy for health endorsement. Se...

  Novel Diagnostic Biomarkers in Liver Disease-a Metabolomic Review Abstract Disease of the liver are complex and pose significant challenges to physician due to diagnostic difficulty requiring invasive techniques such as liver biopsy. Changes in the odour of human excretions could provide diagnostic insight into pathophysiological imbalance. Identifying underlying volatiles metabolites responsible for these odorous changes can be correlated with the pathological process within the body. Advances in the technology have enabled us to interpret the volatile signature of these changes in the odour. This has opened a promising area to lay the foundations of a rapid, non-invasive and point of care diagnostic tool. This review explores the diagnostic potential of volatile organic metabolites as novel biomarkers and extends the discussion on the clinical applications of these biomarkers in liver disorders. Keywords:  Non-invasive biomarkers; Volatile organic metabolites; Liver disord...

  Carcinoma of the Faacial Skin among Yemenis; (A Prospective Hospital-Based Study) Abstract Objective:  The study aimed to study facial skin carcinoma among Yemenis to determain, the types, sites, the relation of this disease to the age and gender, and to define the possible risk factors associated with development of facial skin carcinoma. Material and Methods:  The study is a prospective descriptive hospital based- study carried out at Al-gomhori –Teaching Hospital in Sana’a Republic of Yemen. The material consisted 126 cases of Yemen patients who attending to the department of oral and maxillofacial surgery and to the consultant unit of the head and neck surgery and diagnosed clinically, radiographically and histopathologically as having facial skin carcinoma. Patients who had previous treatment (surgical, radiation or chemo - therapy) or who had recurrent cancer were excluded. Data: were collected from history (using a questionnaire sheet), clinical examination of pa...