BiomedGrid

  Hyperglycemia Damages the Endothelial Glycocalyx: Implications for The Blood Brain Barrier Abstract The glycocalyx is a matrix of proteoglycans, glycoproteins, glycosaminoglycans, glycolipids and soluble proteins that coats the endothelial cells, together with the endothelium, the astrocyte end feet and basement membrane, contributes to the blood brain barrier, which prevents large molecules, neurotoxins, inflammatory factors and pathogens into the brain. It has been demonstrated that hyperglycemia results in damage to the glycocalyx through mechanisms that are still being elucidated. This means that the brain may be exposed to harmful agents that can cause multiple diseases. More studies are therefore needed to understand and prevent brain disease due to hyperglycemia. Keywords:  Hyperglycimia; Diabetes; Brain; Blood brain barrier; Endothelium; Glycocalyx; Cerebrovasculature Introduction It is well established that diabetes can lead to cerebral vasodegeneration, manifested ...

  Monitoring of Some Organophosphorus and Organochlorine Pesticides Residue in Beef Meat from Khartoum State Slaughterhouses Abstract Background:  Organochlorine and Organophosphorus Pesticides are found in the environment in small concentrations, but they have cumulative characteristics thus become a threat to human health and life. This study is focused on detection and determination of some of these pesticides in bovine muscles, meat in two main slaughterhouses in Khartoum state. Materials and methods:  50 samples were collected in sterile bags, transferred to the lab, samples were extracted within 24 hours of collection using mixture hexane and acetone, followed by partitioning and drying the samples using rotary evaporator at 40ºC. clean up step was achieved using silica gel column previously washed with hexane. Pesticides residues read against standards using GC-FID. Results:  seventy-two percentage of samples obtained from slaughterhouse one was positive, whil...

  Fresh Herbage Marketing at Kwalkwalawa Market during Dry Season in Sokoto, Nigeria Abstract This study was conducted to document the supply and use of fresh herbage of various types for dry season feeding of animal by livestock farmers in kwalkwalawa, Sokoto, Nigeria. The objective of the study was to study socio-economic characteristic of the fresh herbage sellers and buyers at kwalkwalawa village market, to identify the types, source and mode of transportation of fresh herbage sold at kwalkwalawa village market and describe the patterns of supply and demand of the fresh herbage at the kwalkwalawa village market. The study was conducted at kwalkwalawa village of Dundaye district of wamakko local government area where the herbage market is located. Information of this research was collected using two different questionnaires. A and B questionnaires was administered to sellers and buyers of fresh herbage respectively. A total of 44 respondents were covered with 22 from each seller...