BiomedGrid

  Features of Coping Behavior of Tuberculosis Patients Annotation According to the results of the study of psychological and social characteristics of patients with tuberculosis, as well as the results of the survey on the targeted author’s questionnaire presents the features of coping behavior of patients with tuberculosis. Keywords:  Strategies of Coping Behaviour; Psychological Characteristics of Tuberculosis Patients; Social Characteristics of Tuberculosis Patients; Directions of Psychological and Social Correction Introduction The bloodiest war has not claimed as many lives as tuberculosis. For many centuries it has accompanied humanity. Modern methods of genetic diagnosis revealed traces of tuberculosis in mummies of Egyptian pharaohs. Pulmonary tuberculosis is an infectious disease, the causative agent of which is Mycobacterium tuberculosis or Koch’s wand. Even now, with modern advances in medicine, patients die from this disease. Tuberculosis is a chronic infection wit...

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Cognitive Dissonance in Iranian Multiple Sclerosis Patients Abstract Multiple Sclerosis is a chronic disease characterized by loss of myelin in neurons. Objective:  The aim of this study was to compare the cognitive dissonance of multiple sclerosis (MS) patients with healthy people. Methodology:  MS participants were selected using non-probability sampling method from Iranian patients and healthy participants were paired with MS sample in education, age and illness stage. They were asked to complete dissonance arousal and reduction questionnaire (Harmon- Jones;2008). Discussion:  The results showed that the average score of MS patients was significantly higher than non-clinical subjects (p<0.05). It can be stated that one of the basic reasons of dissonance cognition in MS referred to probably impairment of memory, learning and cognitive functions. Discussion:  The results showed that the average score of MS patients was significantly higher than non-clinical subje...

  Underutilization of the Subcutaneous Route of Administration Introduction Therapeutic proteins have become an important part of treatment, particularly for serious and chronic diseases, and the subcutaneous (SC) route of administration has become a more popular, yet still underutilized mode of delivery. The extracellular matrix of the hypodermis is composed of a network of fibrous proteins (e.g., collagen and elastin) embedded within a viscoelastic gel. The viscoelastic gel is composed of glycosaminoglycans and proteoglycans that create resistance to bulk fluid flow in the SC space. The primary glycosaminoglycan is the highly hydrated hyaluronan, a mega-dalton polymer of repeating disaccharide units of N-acetylglucosamine and glucuronic acid. Following SC injection of water-soluble small molecules, absorption into the systemic circulation occurs via local capillaries. In contrast, large molecules (e.g., proteins) reach the systemic circulation via bulk fluid flow into draining ly...

  Post-vaccination epidemiological analysis of hepatitis “B” viral infection among selected communities in the Central region of Ghana Abstract Introduction:  Hepatitis B viral infection (HBV) remains a global health threat. About 257 million people currently living with HBV worldwide. HBV is prevalent in sub-Saharan Africa with prevalence of >8% established including West Africa. Though Anti-HBV vaccines existed since 1982, as the single most important Hepatitis B prevention measure. Ghana started active mass immunization program on HBV in infants in 2002 with single- combined Expanded Program Immunization (EPI) (pentavalent vaccine). However, this do not cover persons outside the EPI especially Adults. We designed this study to evaluate the impact of this vaccination programs, the accessibility of vaccines and the scope of this program in selected communities in the central region of Ghana. Methods:  We screened and evaluated 1021 respondents from five Ghanaian indig...

  Steroid-Induced Osteoporosis; At a Glance Steroid-Induced Osteoporosis and the Facts Due to its strong immunosuppressive effects, steroids are a valuable group of drugs and are widely used in the treatment of inflammatory and autoimmune diseases. With the discovery of cortisone and cortisol in the 1930s, synthetic derivatives of glucocorticoids are used successfully in many fields of medicine such as rheumatology, allergy, lung diseases, dermatology, hematology [ 1 ], Glucocorticoids (GC) in the treatment of many inflammatory conditions plays an important role. Nowadays steroids major reasons for its use; rheumatologic causes such as rheumatoid arthritis, polymyalgia rheumatica, asthma and chronic obstructive pulmonary disease. It has been reported that oral steroid use in the population is between 0.5-0.9%. The use of GC in the 70-79 age group is approximately 2.5%. [ 2 ]. During chronic use of steroids, well-known side effects such as diabetes, osteoporosis, myopathy, cataract,...