Biomedical Science & Research Journals | Individual Approach to Hormone Replacement Therapy – A Computer Assisted Method of Assessment of the Minimal Useful Dose


Estrogen replacement therapy (ERT) was primarily used to treat vasomotor symptoms, it had been increasingly viewed as a way to prevent chronic diseases of aging, including coronary heart disease (CHD), cognitive impairment and osteoporosis [1-3]. Osteoporosis leads to bone fractures. Death rate due to osteoporosis is higher than the mortality rate attributed to breast and endometrial cancer combined. Estrogens are considered the gold standard in assessing the efficacy of various medications in osteoporosis treatment [1,2]. At least 40% of postmenopausal women in the United States were using ERT before the publication of the Women’s Health Initiative (WHI) report, which addressed the risks and benefits of ERT [1,4]. WHI trials addressed the most commonly used hormone formulations at the time in the United States -- conjugated equine estrogen (CEE) plus medroxyprogesterone acetate (MPA). Findings from these trials have been extensively published during the past decades [5-7].

To view fulltext of article: https://biomedgrid.com/fulltext/volume1/individual-approach-to-hormone-replacement-therapy-a-computer-assisted-method-of-assessment-of-the-minimal-useful-dose.ID.000507.php

Comments

Post a Comment

Popular posts from this blog

Biomedical Science and Research Journals | Simulation Programs in Disaster Medicine

Image
  Simulation Programs in Disaster Medicine Introduction The Significance Soft Abilities in the services of disaster medicine Soft skills are characterized as the individual qualities that empower a person to communicate adequately and harmoniously with others in stuff conditions and are fundamental for effective execution in any relational setting. According to Abbas [ 1 ] these properties are much more pivotal in the medical services industry of disaster medicine and not only, where therapeutic experts and representatives more nearly collaborate with patients and different human groups, as a rule under to great degree troublesome and passionate conditions. Accordingly, people work in disaster medicine issues should completely screen work possibility to guarantee they have the delicate aptitudes required to convey an outstanding level of care and administration to patients, while additionally having the capacity to effectively team up with staff individuals to boost hierarchical vi...
Read more

Biomedical Science and Research Journals | Phosphatidylethanol (PEth); the Superior Direct Alcohol Biomarker against Mean Corpuscular Volume (MCV), Aspartate Amino Transferase (AST), Alanine Aminotransferase (ALT), Gamma-Glutamyl Transferase (GGT) and Carbohydrate-Deficient Transferrin (CDT)

Image
Phosphatidylethanol (PEth); the Superior Direct Alcohol Biomarker against Mean Corpuscular Volume (MCV), Aspartate Amino Transferase (AST), Alanine Aminotransferase (ALT), Gamma-Glutamyl Transferase (GGT) and Carbohydrate-Deficient Transferrin (CDT) Editorial As ethanol itself is metabolised and excreted quickly from the body, assessing alcohol consumption with a blood test relies on other markers indicative of consumption. Traditional tests include Liver Function Testing (LFT), Carbohydrate Deficient Transferrin (CDT) Testing, and a Full Blood Count (FBC). Phosphatidylethanol (PEth) testing, on the other hand, is a direct biomarker of alcohol consumption, can only be detected when alcohol has been consumed, and is directly correlated with the level of alcohol consumed There are some difficulties when testing alcohol in blood to determine if alcohol had been abused. Due to these challenges in testing alcohol consumption behaviours across society, in the most recent decade...
Read more

Biomedical Science and Research Journals | The Effect of User Charges on the Pattern of Health Care Demand in Nigeria

Image
  The Effect of User Charges on the Pattern of Health Care Demand in Nigeria Abstract The economic downturn in early 1980s in Nigeria led to the introduction and implementation of user charges in government health care facilities. This coupled with the persistent poverty level in Nigeria raises the question of consumers’ ability and willingness to pay these user charges. Accordingly, using primary data, this study examined the possible trade-off between user charges and demand for government health services in Nigeria. The analysis showed that increasing user fees substantially reduced the use of government health facility by low-income earners. Thus, it was recommended, among others, that government should introduce price discrimination into user fees, to be set at marginal cost. This would help avoid the adverse distribution effects of user-fees, especially, on the lower income group. Keywords:  User Charges; Demand for government health services; Willingness to pay and Heal...
Read more