Biomedical Scinece and Research Journals | Pore-Forming M2 Domains of CHRNA4 and CHRNB2 Mutations In Autosomal Dominant Nocturnal Frontal Lobe Epilepsy (ADNFLE) Phenotype

Autosomal Dominant Nocturnal Frontal Lobe Epilepsy (ADNFLE) is an uncommon form of epilepsy which causes partial seizures that usually occur at night and almost exclusively during sleep which are characterized by brief tonic or hyperkinetic motor activity without alteration in consciousness. There is some specific cholinergic receptor, nicotinic genes which their mutations can cause ADNFLE like CHRNA2, CHRNA4 and CHRNB2. In this study we have reviewed the effects of Pore-forming M2 domains of CHRNA4 and CHRNB2 genes in occurrence of ADNFLE.

Autosomal Dominant Nocturnal Frontal Lobe Epilepsy (ADNFLE) is an uncommon form of epilepsy which its seizure characteristics tend to occur in clusters - brief motor episodes with hyperkinetic and dystonic features or tonic manifestations. ADNFLE as a focal epilepsy syndrome is described with a single gene inheritance pattern. Its onset ranges from infancy to adulthood although late childhood – about seven to twelve years of age – is the main onset time. Usually the first seizure occurs before the age of twenty and the men and women can be equally affected. 
 
To view fulltext of article:https://biomedgrid.com/fulltext/volume1/pore-forming-m2-domains-of-chrna4-and-chrnb2-mutations-in-autosomal-dominant-nocturnal.000547.php

For More information: biomedical open access Journals: https://biomedgrid.com/index.php
biomedical and science journals

Comments

  1. Anderson RichardFebruary 22, 2022 at 6:35 PM

    Natural herbs have treated so many illnesses that drugs and injections can't treat. I've seen the great importance of natural herbs and the wonderful work they have done in people's lives. I read people's testimonies online on how they were treated of HSV, HPV, Herpes, Liver diseases, Anxiety, Fever ,diarrhoea, aches and pains, sore throat , etc , by natural medicine, so I decided to contact the Naturopath Dr because I know nature has the power to heal anything. Believe it or not. but I am a living testimony. There is no harm trying natural herbs. Contact Dr on Whats-App . +233502715551. text/call via: +1 (719) 629 0982 ,For herbs and medications. Or you can also contact through his Facebook page @ Dr Chike Herbal Remedy.

    ReplyDelete

Post a Comment

Popular posts from this blog

Biomedical Science and Research Journals | Advanced Applications of Biomaterials Based on Alginic Acid

Advanced Applications of Biomaterials Based on Alginic Acid Abstract Alginic acid, also known as algin or alginate, is a natural carbohydrate, which is derived from marine brown algae, as well as some microorganisms. It can be used in various applications. In particular, alginate has shown great potential in the areas of wound healing, drug delivery, in vitro cell culture, and tissue engineering, allowing the categorization of it as a promising biomaterial, or a basic component of other biomaterials. The unique characteristics of alginic acid, such as the biocompatibility, the mild required gelation conditions, the low toxicity, the relative low cost and the simple modifications, allow the development of alginate hydrogels, and alginate derivatives with enhanced properties. The aim of this review, is to present an overview of the properties of alginate, shedding light on the current and potential applications and suggesting new perspectives for future studies. Introduction Innovative b
Read more

Biomedical Science and Research Journals | The Need of Early Detection of Positive COVID-19 Patients in the Community by Viral Tests (e.g. RT-PCR Tests) and Antibody Tests (Serological Tests) to Stop the Spread

Image
  The Need of Early Detection of Positive COVID-19 Patients in the Community by Viral Tests (e.g. RT-PCR Tests) and Antibody Tests (Serological Tests) to Stop the Spread Abstract Background and Objective:  The Aim of this article is to tell the Importance of early testing for COVID-19 novel corona virus of the suspected communities. The earlier to find out the Positive results of the COVID-19 novel corona virus more robust preventions against COVID-19 could be implemented. Methods:  The Author of this article has randomly selected 15 Articles from PUBMED Central and others sources with search word COVID-19 Test Kits. After reviewing the research articles and looking at their results it clearly shows the Importance of use of COVID-19 Test Kits. The earliest the use of COVID-19 Test Kits it prevents the whole community from getting infection from infected people. The Positive people with COVID-19 Test Kits would be Quarantined and treated in the health facilities or at home depending upo
Read more

Biomedical Science and Research Journals | Banking Progenitor Cells for Hippiatric Regenerative Medicine: Optimized Establishment of Safe and Consistent Cell Sources for Standardized Veterinary Therapeutic Protocols

Image
  Banking Progenitor Cells for Hippiatric Regenerative Medicine: Optimized Establishment of Safe and Consistent Cell Sources for Standardized Veterinary Therapeutic Protocols Abstract Acute musculoskeletal injuries in large animals such as horses or camels often result in productivity losses and euthanasia in racing, esthetic or stock animal industries. Bioengineered products for tissue reconstruction and wound healing may supplement traditional veterinary surgical care synergistically. Banked primary fetal progenitor cells can potentially be used towards structural and functional therapeutic restoration in condensed timeframes. Extensive clinical experience exists in our University Hospital working with dermal progenitor fibroblasts for managing burns, donor site grafts and ulcers. By extrapolation, the present study assessed suitability of equine fetal progenitor cell sources for biotechnological processing, robust cell banking and application in tissue engineering strategies for hip
Read more