Biomedical Scinece and Research Journals | Photodynamic Therapy for the Treatment of Oral HPV Lesion in a Patient with Oral Lichen Planus. A Case Report

Human papilloma viruses (HPVs) are a group of double-stranded DNA, that cause different type of lesions, also on oral cavity. Lichen planus (LP) is a chronic inflammatory mucocutaneous disease affecting the oral cavity and skin. Photodynamic therapy (PDT) is a treatment used in all fields of medicine, based on the interaction between a photosensitizer, the appropriate wavelength, and oxygen. The reaction generates ROS in cells that take up the photosensitizer, causing cell death by necrosis or apoptosis. Different parameters are described in the literature for PDT. 

We would like to report a case of a patient with diagnosis of Oral lichen planus that developed, and HPV lesion treated with a particular type of PDT. I have not found other cases of Photodynamic Therapy for the treatment of oral HPV lesions, in the scientific literatureHuman papilloma viruses (HPVs) are a group of double-stranded DNA. Human Papillomavirus (HPV) infection is considered the most common sexually transmitted infection. About 6 million people are diagnosed each year and approximately 9.0- 13.0% of the world population is already infected with the disease [2]. There are a lot of subtypes of HPV (more than 120), and some of these HPV plays a role in the pathogenesis of Head and Neck Squamous Cell Carcinomas and Oropharyngeal Squamous Cell Carcinoma. Different types of HPV lesions could occur in oral cavity.

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