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AJBSR FAQs: Key Answers to Biomedical Research and Publishing Questions

 AJBSR FAQs: Key Answers to Biomedical Research and Publishing Questions Q: What are the Manuscript Guidelines in Open Access AJBSR? A: The Manuscript Guidelines for the American Journal of Biomedical Science & Research (AJBSR) provide detailed instructions for authors preparing their submissions. The manuscript should be structured as follows: a Title Page including the manuscript title, authors' names, affiliations, and contact information for the corresponding author; an Abstract summarizing the research in 150-300 words with key findings; 3-6 Keywords reflecting the main topics; an Introduction outlining the background, reasons, and objectives; Materials and Methods detailing the study design and procedures for replication; Results presenting findings with appropriate tables and figures; a Discussion interpreting the results and their significance; a Conclusion summarizing main findings and implications; Acknowledgments for contributors, funding sources, or institutions; ...
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Biomedical Science and Research Journals | Rapid Induction of Orthotopic Hepatocellular Carcinoma in Mice by Fixed Puncture Point Injection

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  Rapid Induction of Orthotopic Hepatocellular Carcinoma in Mice by Fixed Puncture Point Injection Abstract Aim:  Animal model is an indispensable tool in investigating the development, progression and treatment of human cancer including hepatocellular carcinoma (HCC). However, it is still challenging in establishing orthotopic HCC mouse models. Here, we presented a minimally invasive method with high tumor formation rate in mouse liver. Methods:  Hep3B-luc and SNU-449-luc HCC cells mixed with Matrigel were injected into the liver of nude mice from different source at fixed injection site and depth, respectively. The mice were divided into 3 groups. At fifteen days post-injection, the bioluminescence signal of liver tumor was detected and tumors in injected mouse liver were harvested. Cons and pros were then compared between presented and common approaches. Results:  We successfully developed an orthotopic transplantation tumor model in nude mice by directly injectin...
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